In May 1979, St. Luke's Hospital, Presbyterian Denver Hospital, and Presbyterian Aurora Hospital merged their business and financial operations into a new nonprofit organization called Presbyterian Denver/St. Luke's Healthcare Corporation.

The Colorado Episcopal Foundation was established in 1983.  The initial incorporators were Joan D. Francis, Ranald Macdonald & E. M. Womack. In April 1984 they adopted the initial mission statement: "Provide special financial support for the work of Christ through the Episcopal Church in Colorado.” In December 1985, Bill Crews was hired as the first executive director. He began leading the Foundation in February of 1986.

The current executive director, Scott Asper, stepped into this role in 2017, yet he has been working with the Foundation for many years. He is a certified accountant and he is dedicated to his position. Although the programs within the Foundation may have changed or shifted over the years, the core principle of strengthening the capacity for mission and ministry by stewarding the financial resources of the  Episcopal Church in Colorado has remained.